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 What is Glyxambi?

Glyxambi (empagliflozin and linagliptin) is a sodium-glucose cotransporter (SGLT2) inhibitor and an inhibitor of dipeptidyl peptidase-4 (DPP-4) enzyme. It can be used as an auxiliary means of diet and exercise to improve blood sugar control in patients. Among adults with type 2 diabetes

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What are the side effects of Glyxambi?

Common side effects of Glyxambi include:

  • Urinary Tract Infection
  • Common cold symptoms
  • Upper respiratory tract infection
  • Reproductive yeast infection
  • Increased urination
  • Joint pain
  • nausea
  • Runny or stuffy nose
  • diarrhea
  • cough
  • Elevated blood cholesterol or fat
  • diarrhea
  • Glyxambi dosage
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The recommended dose of Glyxambi is once a day, once a day, with or without food 10 mg empagliflozin/5 mg linagliptin. In patients who tolerate Glyxambi, the dose can be increased to 25 mg empagliflozin/5 mg linagliptin once a day.

Which drugs, substances or supplements interact with Glyxambi?

Glyxambi may interact with diuretics and potent P-gp or CYP3A4 inducers. Tell your doctor about all medicines and supplements you use.

Glyxambi during pregnancy and breastfeeding

During pregnancy, Glyxambi should only be taken if prescribed. Whether the drug passes into breast milk is unclear. Consult your doctor before breastfeeding.

Additional Information

Our Glyxambi (empagliflozin and linagliptin) side-effect drug center will fully introduce the available drug information of potential drugs when taking the drug.

If you have signs of an allergic reaction, seek emergency medical assistance: hives, itching, peeling or peeling; difficulty swallowing, breathing difficulties; swelling of the face, lips, tongue or throat.

If you have rare but serious signs of a genital infection (penis or vagina), seek immediate medical attention: burning, itching, odor, discharge, pain, tenderness, redness or swelling, fever, discomfort in the genital or rectal area. These symptoms may get worse quickly.

If you have the following conditions, stop taking this medicine and call your doctor immediately:

Severe or persistent joint pain;

Severe skin reactions-itching, blisters, rupture of the outer layer of the skin;

Ketoacidosis (too much acid in the blood)-nausea, vomiting, stomach pain, confusion, abnormal drowsiness or difficulty breathing;

Pancreatitis-severe pain in the upper abdomen spreads to the back, nausea and vomiting, rapid heart rhythm;

Dehydration symptoms-dizziness, weakness, dizziness (like you might faint);

Signs of bladder infection-pain or burning when urinating, blood in the urine, pelvic or back pain; or

Symptoms of heart failure-shortness of breath (even when lying down), swelling of legs or feet, rapid weight gain.

Common side effects may include:

  • Sore throat; or
  • Runny nose, stuffy nose, sinus pain.

side effect
  • The following important adverse reactions are described below and elsewhere in the label:

  • Pancreatitis [see warnings and precautions]
  • Heart failure [see warnings and precautions]
  • Low blood pressure [see warnings and precautions]
  • Ketoacidosis [see warnings and precautions]
  • Acute kidney injury and renal impairment [see warnings and precautions]
  • Uremia and pyelonephritis [see warnings and precautions]
  • Hypoglycemia with insulin and insulin secretagogues at the same time [see warnings and precautions]
  • Perineal necrotizing fasciitis (Funier's gangrene) [see warnings and precautions]
  • Genital fungal infections [see warnings and precautions]
  • Allergic reaction [see warnings and precautions]
  • Elevated low-density lipoprotein cholesterol (LDL-C) [see warnings and precautions]
  • Severe and disabling joint pain [see warnings and precautions]
  • Bullous pemphigoid [see warnings and precautions]
  • Clinical trial experience
  • Because clinical trials are conducted under widely different conditions, it is impossible to directly compare the adverse reaction rate observed in the clinical trial of one drug with the adverse reaction rate observed in the clinical trial of another drug, and it may not be possible Reflects the adverse reaction rate observed in practice.

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